“A recently published small study addresses Sputnik vaccine’s efficacy against Omicron variant deliberately using serum samples that are not representative. For example, this study used Sputnik samples with a lower virus neutralization ability against SARS-COV-2 than AstraZeneca’s vaccine while a much larger study in Argentina based on representative serum samples demonstrated 1.8 times higher virus neutralizing titers against SARS-COV-2 for Sputnik, which is explained by its heterologous boosting advantage. Therefore, conclusions about Sputnik efficacy against Omicron based on wrong serum samples, cannot be made. Within the next 7 days the Gamaleya Center will publish its own positive data based on representative serum samples on Omicron neutralization ability for both Sputnik V vaccine and one-shot Sputnik Light as a booster.
In other studies with representative samples Sputnik also induced a stronger and long lasting T-cell immunity, showing an 80% efficacy against Delta on months 6-8 compared with efficacy of less than 29% demonstrated by mRNA vaccines after 6 months.”
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